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| номер сообщения: 49-54-34144 |
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Тоже в общем-то считает, что иммунизировать нужно летом, но дело в Британии и теперь уже индийским вариантом. Проблема лишь в том, что в Британии недостаток вакцин и не все, кто хотел, вакцинировался. Поэтому за них приходится делать выбор.
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| номер сообщения: 49-54-34145 |
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No shirts, pants or undies for Philly Naked Bike Ride -- but masks required
Philadelphia bike riders won’t need their shirts, pants, skirts or even underwear — just a mask.
Organizers of the annual Philly Naked Bike Ride say this year’s event will take place Aug. 28 and will require masks, based on the city's earlier coronavirus restrictions.
The city lifted most of its COVID-19 rules this week, citing an increase in vaccinations and a decrease in cases. But ride organizers said they hadn't had a chance to chat since the city's guidelines changed so for the time being, they're “going to stick with our initial mask guidance.” |
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| номер сообщения: 49-54-34147 |
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| номер сообщения: 49-54-34148 |
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| номер сообщения: 49-54-34149 |
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| номер сообщения: 49-54-34150 |
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"Virologist Julian Tang, of Leicester University, said that from an evolutionary viewpoint, if a virus is more transmissible, it tends to be less severe.": no, those models of viral evolution have been replaced by more modern tradeoff models.
These models show that some level of pathogenicity is frequently required for spread. If a virus can only spread by being somewhat pathogenic (e.g. respiratory viruses that make you cough) then viruses will be selected to become more pathogenic, not less.
Good case in point is the furin cleavage site insertion that allowed the zoonotic jump from bats to humans, and which makes it more transmissible, but also more deadly. So there is positive pleitropy between transmissibility & pathogenicity in SARS-CoV2.
The B.1.617 Indian variants carry the P681R mutation in the spike gene, which makes furin cleavage site extra-polybasic (adding another arginine:PRRAR->RRRAR), which makes it easier to cleave by furin & enter your cells. Increased pathogenicity expected.
So it is no surprise, and in line with evolutionary theory, that the B.1.617.2 / Delta variant appears to be associated with an increased risk of hospitalisation.
If SARS-CoV2 will eventually become a common cold, it will not be because of intrinsic viral evolution, but because sooner or later we will all have been vaccinated or have been in contact with the virus. And because many will catch it as a child, where symptoms are less severe. |
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| номер сообщения: 49-54-34151 |
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На этот счёт Анжела высказывалась недавно.
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| номер сообщения: 49-54-34152 |
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| Там ссылка на целую статью еще 1994 года - Virulence |
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| номер сообщения: 49-54-34153 |
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grizly:
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All age groups у них начинаются с 55 |
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| номер сообщения: 49-54-34154 |
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| номер сообщения: 49-54-34155 |
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Variant exploding in U.K. accounts for 6 percent of U.S. infections, White House says
Недели две-три назад кажется было 1%. Хотя здесь побольше.
В Британии доля удваивалсь за 8 дней. Т.е. через месяц-два, может начать приводить к увеличению числа случаев, если недостаточно вакцинированных. Сейчас, кажется стали относительно халатно относиться к тестированию, так что можно будет судить наверно только по госпитализациям, а это может быть еще +месяц из-за возрастного состава. |
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| номер сообщения: 49-54-34158 |
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| номер сообщения: 49-54-34159 |
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| номер сообщения: 49-54-34160 |
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| номер сообщения: 49-54-34161 |
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| номер сообщения: 49-54-34162 |
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Sinovac, Pfizer/BioNtech COVID-19 vaccines prove highly effective in Uruguay -government
Uruguay on Tuesday released real-world data on the impact of Sinovac Biotech's (SVA.O) COVID-19 vaccine among its population that showed it was over 90% effective in preventing intensive care admissions and deaths.
The shot reduced deaths by 95% and intensive care admissions by 92%, and also showed 61% efficacy in cutting coronavirus infections, the government said.
A total of 795,684 people - health workers and members of the general population between the ages of 18 and 69 - at least 14 days after receiving their second dose of Sinovac's CoronaVac were compared to unvaccinated people to determine the real-world vaccine effectiveness, the government said in a report.
The government also studied the effectiveness of the Pfizer/BioNTech (PFE.N), vaccine among 162,047 health workers and people over 80 years old. The shot was 94% effective at preventing intensive care unit admissions and deaths, and reduced infections by 78%, the report said.
Overall, intensive care hospitalizations and deaths from COVID-19 dropped by more than 90% among Uruguayans who were fully-inoculated, the data showed. |
В Уругвае вроде бы P.1 должен быть |
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| номер сообщения: 49-54-34163 |
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| номер сообщения: 49-54-34164 |
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Meaghan Kall @kallmemeg 20h
New @PHE_uk reports now published
33,207 total cases of Delta variant this week
You may notice - a dramatic increase from 9,426 last week
Most of this is due to cases detected using *new* genotyping assay, which uses a highly specific mutation as an indicator of a Delta variant. Normal sequencing has a reporting delay 7-21 days. Genotyping assay has a ~36 hour turnaround |
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| номер сообщения: 49-54-34165 |
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| номер сообщения: 49-54-34166 |
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Кажется они их все уже давно продают, но кроме обнаружения британского варианта они ни для какого другого широко не использовались.
А здесь вот сразу на 3 VOC делали, может и не только они |
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| номер сообщения: 49-54-34167 |
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| номер сообщения: 49-54-34168 |
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Словакия отказалась от новых закупок «Спутника V»
Власти Словакии не планируют снова закупать российскую вакцину от коронавируса нового типа «Спутник V», сообщил министр иностранных дел страны Иван Корчок.
«Сегодня мы видим, что количество тех, кто хотел бы пройти вакцинацию «Спутником», значительно снизилось», — заявил глава словацкого МИДа.
По его словам, на данный момент интерес к вакцинации российским препаратом проявили от 5 до 6 тыс. человек, при этом в стране имеется запас из 200 тыс. доз «Спутника V» и необходимости в закупке дополнительных доз нет. |
А говорили, что 15% хочет только Спутник |
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| номер сообщения: 49-54-34169 |
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| Он EMA пока не признан, со всеми вытекающими. |
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| номер сообщения: 49-54-34170 |
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| По идее эти 15% должнны были твердо знать, что Спутник самая лучшая в мире вакцина, а ЕМА не одобряет ее исключительно по политическим соображениям. |
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| номер сообщения: 49-54-34171 |
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| Хорошо б ещё пограничники это знали. |
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| номер сообщения: 49-54-34172 |
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China Returns to Its Strict Covid Limits to Fight a New Outbreak
The latest cases have been found in Guangzhou, capital of the southern province of Guangdong. The authorities have blamed the Delta variant, which has caused widespread loss of life in India.
The city tested practically its entire population of 18.7 million between Sunday and Tuesday, some of them for the second time. It has also put neighborhoods with a total of more than 180,000 residents into total lockdowns, with practically no one allowed out except for medical testing.
The early infections appear to have jumped from person to person at a cluster of eateries. Each infected person has infected more people than in any previous outbreak that China has confronted, Zhang Zhoubin, deputy director of the Guangzhou Center for Disease Control, said at a news conference.
“The epidemic faced by Guangzhou this time is an unprecedented opponent, and it requires more resolute and decisive measures to deal with it,” he said. |
In China’s latest outbreak, doctors say the infected get sicker, faster
Patients are becoming sicker and their conditions are worsening much more quickly, doctors told state-run television on Thursday and Friday. Four-fifths of symptomatic cases developed fevers, they said, although it was not clear how that compared with earlier cases. The virus concentrations that are detected in their bodies climb to levels higher than previously seen, and then decline only slowly, the doctors said.
Up to 12 percent of patients become severely or critically ill within three to four days of the onset of symptoms, said Guan Xiangdong, director of critical care medicine at Sun Yat-sen University in the city of Guangzhou, where the outbreak has been centered. In the past, the proportion had been 2 percent or 3 percent, although occasionally up to 10 percent, he said.
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China has uniquely detailed data, however, because it has essentially universal testing in the vicinity of outbreaks, allowing officials to gather detailed information on the extent of cases.
Delta’s spread in southeastern China focuses more attention on the effectiveness of China’s self-made vaccines. The Chinese authorities have not indicated how many of the new infections have occurred in people who had been vaccinated. In some other countries where Chinese-made vaccines are in wide use, including the Seychelles and Mongolia, infections among vaccinated people are rising, although few patients have reportedly developed serious illness. |
Там, кстати, прикольная фотография из центра вакцинации. То ли матрасы им девать некуда, то ли сразу готовят место, куда больных размещать. А может просто какая-то выставка с матрасами используемая для вакцинации |
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| номер сообщения: 49-54-34173 |
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| Roger: Хорошо б ещё пограничники это знали. |
Когда человек говорит, что привьется только Спутником, его не должны останавливать знания чужих пограничников где-то в других странах Европы |
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| номер сообщения: 49-54-34174 |
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| Останавливают не знания, останавливают пограничники. |
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| номер сообщения: 49-54-34175 |
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| А какие пограничники у словаков? Неужели в Украину не пускают? |
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| номер сообщения: 49-54-34176 |
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